Methylation Therapy

The biochemistry of the body needs to be evaluated and addressed whenever their is a fertility concern.  Couples who struggle to conceive have higher rates of methylation impairments.  Methylation is the process by which we produce healthy DNA.  Methylation also promotes healthy hormone regulation and reduces toxic and inflammatory load.  The methylation cycle in the body sits directly next to the folic acid cyle.


This pathway is vital to reproductive health and is blocked by environmental toxins.  Opening up and supporting this pathway for both partners dramatically improves fertility.  We have known about folic acid for over 20 years. Taking folic acid at least 3 months before conception helps prevent neural tube defects. The new research shows that we need 3-5mg of folic acid for optimum support. What is more exciting is that to help folic acid be activated into the ideal form is methyl. This tiny natural bit of chemistry is essential in converting what you take in a pill to what is made in nature and required in your body. If your folic acid is coming from food, it is actually folate that you are injesting and does not require methyl.

Folate can be found in lots of foods:

  • Black eye peas (love the BEPs)
  • Spinach
  • Baked bean
  • Asparagus
  • Northern beans
  • Broccoli
  • Green peas
  • Eggs
  • Rice
  • Avocado

As it would turn out, too much folic acid is not the best thing for the body especially for hormone regulation. Not folate, that you can have as much as you want….but folic acid. We all have so much folic acid in our blood because of supplementation in food or supplements, which is fine and has huge health benefits, but what has even more health benefits on hormone regulation is having balanced folate, methyl and vitamin B12 levels in the body. If we have too little folic acid or too little methyl, B12 and folate then bad things can happen to our hormones.

If a person doesn’t methylate estrogen properly in the liver (a process which breaks down estrogen no longer required by the body and allows it to become water soluble and eliminated in the bowel as waste) then we get some serious hormone problems. Extra bad estrogen floats around in the blood and the body won’t allow that to happen for long so it winds up being bound inside our tissue in the form of:

  • Endometriosis (me)
  • Polycystic Ovarian Syndrome (me)
  • Uterine fibroids
  • Heavy menses
  • Headaches with menses
  • Extremely light and irregular menses
  • Fibrocystic Breasts
  • Those who make lots of follicles when they are using IVF
  • Acne and unwanted hair growth
  • Insulin sensitivity (can’t lose weight)

Methylation happens in the liver and can be optimized by supplementing with methly-B12 or Methlycobalamin.  It turns out, we all have a ton of folic acid, especially those who are trying their best to have a baby. So to balance all that effort, why not try to up the natural folate in the diet and make the discrepancy in the body with a safe methyl-B12. This support is water soluble and safe and if your body does not need it, you will urinate it out.

Bad estrogen must come out of the body in order to balance your hormones. The leverage we have over our hormones is our digestive system or our elimination system (because we want to eliminate bad estrogen) the problem is that now they are stuck inside your tissues and have to come out.

Methyl-B12 therapy is an essential part of the Natural Fertility Program and in some ways the key to it’s success.  B12 treatment speeds the rate of cellular healing allowing a “hypofertile” couple to have much healthier cell status in 3-9 months.